Two warring factions have different translations and interpretations of The Ancient Prophecies. Both interpretations of the Prophecies are occurring, in a spectacular and "biblical plague" fashion, as we approach the ultimate final conflict. Both versions are increasingly vague about the resolution of the prophecy.
Plot points could include, determining how the literary time keeping devises of the The Ancient Prophecies match up with these real life events, war profiteering by mercenaries thanks to widely known accurate predictions of the future, new cults erupting, new magics being discovered now that current events are functioning as a Rosetta-stone to old knowledge, etc. etc.
(Mostly plagiarized from BSG.)